{"id":4214,"date":"2023-06-14T10:01:58","date_gmt":"2023-06-14T08:01:58","guid":{"rendered":"https:\/\/t21learning.institutlejeune.org\/?p=4214"},"modified":"2023-11-22T17:02:49","modified_gmt":"2023-11-22T16:02:49","slug":"related-pathologies-of-the-eyes-in-individuals-with-trisomy-21","status":"publish","type":"post","link":"https:\/\/t21learning.institutlejeune.org\/en\/related-pathologies-of-the-eyes-in-individuals-with-trisomy-21\/","title":{"rendered":"Related pathologies of the eyes in individuals with trisomy 21"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4214\" class=\"elementor elementor-4214\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-bcd2501 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"bcd2501\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3d33776\" data-id=\"3d33776\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-739d8ae elementor-widget elementor-widget-text-editor\" data-id=\"739d8ae\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>OPHTHALMOLOGICAL PATHOLOGIES<\/strong><\/p><p><strong>\u00a0<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f3e818e elementor-widget elementor-widget-heading\" data-id=\"f3e818e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Related pathologies of the eye<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-94c524a elementor-widget elementor-widget-spacer\" data-id=\"94c524a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4166f5b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4166f5b\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-a2f6aac\" data-id=\"a2f6aac\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-68055fa elementor-widget elementor-widget-image\" data-id=\"68055fa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"932\" height=\"572\" src=\"https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2023\/06\/consultation2_Anne-Hiance-Delahaye-32.jpeg\" class=\"attachment-large size-large wp-image-3783\" alt=\"pathologies_annexes_oeil\" srcset=\"https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2023\/06\/consultation2_Anne-Hiance-Delahaye-32.jpeg 932w, https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2023\/06\/consultation2_Anne-Hiance-Delahaye-32-300x184.jpeg 300w, https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2023\/06\/consultation2_Anne-Hiance-Delahaye-32-768x471.jpeg 768w\" sizes=\"(max-width: 932px) 100vw, 932px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-a45ba83\" data-id=\"a45ba83\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-932f368 elementor-widget elementor-widget-toggle\" data-id=\"932f368\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1541\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1541\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">CHAPTER OUTLINE<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1541\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1541\"><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/the-eye-and-vision-in-individuals-with-trisomy-21\/\">1- The eye and vision<\/a><\/p><p>\u00a0<\/p><p><strong><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/related-pathologies-of-the-eyes-in-individuals-with-trisomy-21\/\">2- Related pathologies of the eye<\/a><\/strong><\/p><p>\u00a0<\/p><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/vision-disorders-trisomy-21\/\">3- Vision disorders<\/a><\/p><p>\u00a0<\/p><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/anterior-segment-eye-diseases-trisomy-21\/\">4- Anterior segment eye diseases<\/a><\/p><p>\u00a0<\/p><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/posterior-segment-eye-diseases-in-individuals-with-trisomy-21\/\">5- Posterior segment eye diseases<\/a><\/p><p>\u00a0<\/p><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/neuro-ophthalmology-and-trisomy-21\/\">6- Neuro-ophtalmology<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-da3cd7c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"da3cd7c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-18c48beb\" data-id=\"18c48beb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6b33d20 elementor-widget elementor-widget-spacer\" data-id=\"6b33d20\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3acff4c elementor-widget elementor-widget-text-editor\" data-id=\"3acff4c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Among ophthalmological pathologies, which are more prevalent in people with Down&#8217;s syndrome, several affect the eye&#8217;s appendages. These include congenital palpebral malposition (the most common ocular anomaly in Down&#8217;s syndrome, which can lead to chronic damage to the cornea or conjunctiva, or even amblyopia), inflammatory eyelid pathologies (also frequent), and congenital obstructions of the nasolacrimal passages (more common in children).<\/p><p>\u00a0<\/p><p>Dr. Herv\u00e9 Walti, a pediatrician at the Institut J\u00e9r\u00f4me Lejeune, describes these different pathologies in the video and the accompanying data sheet. Discover the entire &#8220;Ophthalmological pathologies&#8221; chapter by clicking on the links on the right of the page.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-985d68f elementor-widget elementor-widget-spacer\" data-id=\"985d68f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ed6e280 elementor-widget elementor-widget-video\" data-id=\"ed6e280\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/youtu.be\\\/zOQr5x_7M9E&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-91d504d elementor-widget elementor-widget-spacer\" data-id=\"91d504d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4e91fc8 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"4e91fc8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2023\/08\/3.2-Pathologies-of-the-Ocular-Adnexa-EN.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Download the Summary Sheet<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-acfb06f elementor-widget elementor-widget-spacer\" data-id=\"acfb06f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-09d9e5d elementor-widget elementor-widget-text-editor\" data-id=\"09d9e5d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Discover below the presentation associated with this video on the subject of &#8220;Ophthalmological pathologies&#8221;.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-67fc6d2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"67fc6d2\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-adc6cf2\" data-id=\"adc6cf2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-08d0a3a elementor-widget elementor-widget-spacer\" data-id=\"08d0a3a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f2192a7 elementor-widget elementor-widget-shortcode\" data-id=\"f2192a7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\"><div class=\"_df_book df-lite\" id=\"df_4182\"  _slug=\"3-2-les-pathologies-des-annexes-de-loeil-en\" data-title=\"3-2-les-pathologies-des-annexes-de-loeil-en\" wpoptions=\"true\" thumbtype=\"\" ><\/div><script class=\"df-shortcode-script\" nowprocket type=\"application\/javascript\">window.option_df_4182 = {\"outline\":[],\"autoEnableOutline\":\"false\",\"autoEnableThumbnail\":\"false\",\"overwritePDFOutline\":\"false\",\"direction\":\"1\",\"pageSize\":\"0\",\"source\":\"https:\\\/\\\/t21learning.institutlejeune.org\\\/wp-content\\\/uploads\\\/2023\\\/06\\\/2.-PATHOLOGIES-DES-ANNEXES-DE-LOEIL-DES-PPT21_VFPN-eng.pdf\",\"wpOptions\":\"true\"}; if(window.DFLIP && window.DFLIP.parseBooks){window.DFLIP.parseBooks();}<\/script><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ab8570d elementor-widget elementor-widget-spacer\" data-id=\"ab8570d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f625a75 elementor-align-justify btn-refs elementor-widget elementor-widget-button\" data-id=\"f625a75\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">See references<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-b720bb6 div-refs div-refs-closed elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b720bb6\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-33c594e\" data-id=\"33c594e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-87397c0 elementor-widget elementor-widget-text-editor\" data-id=\"87397c0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>Alaboudi A, Al-Shaikh O, Fatani D, Alsuhaibani AH. Acute dacryocystitis in pediatric patients and frequency of nasolacrimal duct patency. Orbit. 2021.<\/li><li>Ali MJ, Paulsen F. Syndromic and Nonsyndromic Systemic Associations of Congenital Lacrimal Drainage Anomalies: A Major Review. Ophthalmic Plast Reconstr Surg. 2017<\/li><li>Al-Mujaini A, Yahyai MA, Ganesh A. Congenital Eyelid Anomalies: What General Physicians Need To Know. Oman Med J. 2021<\/li><li>Azman BZ, Ankathil R, Siti Mariam I, Suhaida MA, Norhashimah M, Tarmizi AB, Nor Atifah MA, Kannan TP, Zilfalil BA. Cytogenetic and clinical profile of Down syndrome in Northeast Malaysia. Singapore Med J. 2007.<\/li><li>Bansal O, Bothra N, Sharma A, Walvekar P, Ali MJ. Congenital nasolacrimal duct obstruction update study (CUP study): paper I-role and outcomes of Crigler&#8217;s lacrimal sac compression. Eye (Lond). 2021.<\/li><li>Baran F, Kelly JP, Finn LS, Manning S, Herlihy E, Weiss AH. Evaluation and treatment of failed nasolacrimal duct probing in Down syndrome. J AAPOS. 2014.<\/li><li>Benda CE. Down\u02bcs syndrome: Mongolism and its Management. New York: Grune &amp; Stratton, 1969: 1-30.<\/li><li>Berk AT, Saatci AO, Er\u00e7al MD, Tun\u00e7 M, Ergin M. Ocular findings in 55 patients with Down&#8217;s syndrome. Ophthalmic Genet. 1996.<\/li><li>Coats DK, McCreery KM, Plager DA, Bohra L, Kim DS, Paysse EA. Nasolacrimal outflow drainage anomalies in Down&#8217;s syndrome. Ophthalmology. 2003.<\/li><li>Corredor-Osorio R, Tovilla-Pomar JL, Tovilla-Canales JL. Congenital upper eyelids ectropion in Down&#8217;s syndrome. GMS Ophthalmol Cases. 2017.<\/li><li>da Cunha RP, Moreira JB. Ocular findings in Down&#8217;s syndrome. Am J Ophthalmol. 1996 .<\/li><li>Duffier JL, Kaplan J : Oeil et G\u00e9n\u00e9tique. Paris : Elsevier Masson.<\/li><li>Fimiani F, Iovine A, Carelli R, Pansini M, Sebastio G, Magli A. Incidence of ocular pathologies in Italian children with Down syndrome. Eur J Ophthalmol. 2007.<\/li><li>Fong AH, Shum J, Ng AL, Li KK, McGhee S, Wong D. Prevalence of ocular abnormalities in adults with Down syndrome in Hong Kong. Br J Ophthalmol. 2013.<\/li><li>Guthrie AJ, Kadakia P, Rosenberg J. Eyelid Malposition Repair: A Review of the Literature and Current Techniques. Semin Plast Surg. 2019.<\/li><li>Hu K, Patel J, Patel BC. Crigler Technique For Congenital Nasolacrimal Duct Obstruction. [Updated 2022 May 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK559267.<\/li><li>Kaplan AT, Oral AY, Kaymak NZ, \u00d6zen MC, Simsek S. Analyzing Ocular and Systemic Findings of Patients with Down Syndrome South. Clin. Ist. Euras. 2019.<\/li><li>Karlica D, Skelin S, Culic V, Galetovi\u0107 D, Znaor L, Karlica H, Paveli\u0107 J. The ophthalmic anomalies in children with Down syndrome in Split-Dalmatian County. Coll Antropol. 2011.<\/li><li>Kim JH, Hwang JM, Kim HJ, Yu YS. Characteristic ocular findings in Asian children with Down syndrome. Eye (Lond). 2002.<\/li><li>Kruszka P, Porras AR, Sobering AK et al. Down syndrome in diverse populations. Am J Med Genet A. 2017.<\/li><li>Krinsky-McHale SJ, Jenkins EC, Zigman WB, Silverman W. Ophthalmic disorders in adults with down syndrome. Curr Gerontol Geriatr Res. 2012.<\/li><li>Landau Prat D, Tadros S, Revere KE, Katowitz JA, Katowitz WR. Management of congenital nasolacrimal duct obstruction in down syndrome. Eye (Lond). 2022.<\/li><li>Lee S, Kim N, Khwarg SI, Choung HK, Lee MJ. Congenital lacrimal fistula associated with Down syndrome. Graefes Arch Clin Exp Ophthalmol. 2012.<\/li><li>Lekskul A, Preechaharn P, Jongkhajornpong P, Wuthisiri W. Age-Specific Outcomes of Conservative Approach and Probing for Congenital Nasolacrimal Duct Obstruction. Clin Ophthalmol. 2022.<\/li><li>Liza-Sharmini AT, Azlan ZN, Zilfalil BA. Ocular findings in Malaysian children with Down syndrome. Singapore Med J. 2006.<\/li><li>Ljubic A, Trajkovski V, Tesic M, Tojtovska B, Stankovic B. Ophthalmic manifestations in children and young adults with Down syndrome and congenital heart defects. Ophthalmic Epidemiol. 2015.<\/li><li>Lueder GT. Treatment of nasolacrimal duct obstruction in children with trisomy 21. J AAPOS. 2000.<\/li><li>Medsinge A, Duncan K, Yu JY. The association between epiblepharon and obesity: an experience at tertiary care center in Western Pennsylvania\/North America. Int Ophthalmol. 2021.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5d30cbd\" data-id=\"5d30cbd\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bef89ac elementor-widget elementor-widget-text-editor\" data-id=\"bef89ac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>Miller R, Martin F, Allen H. A case of congenital ectropion in Down&#8217;s syndrome. Aust N Z J Ophthalmol. 1988 .<\/li><li>Mostovoy D, Vinker S, Mimouni M, Goldich Y, Levartovsky S, Kaiserman I. The association of keratoconus with blepharitis. Clin Exp Optom. 2018.<\/li><li>Mu\u00f1oz-Ortiz J, Charry-S\u00e1nchez JD, Bechara-Arango I, et al. Down syndrome: a systematic review Prevalence of ophthalmological manifestations in pediatric and adolescent populations with of the literature. Syst Rev. 2022.<\/li><li>Nelson J, Gigantelli W; Epiblepharon : an association with Hispanic ethnicity. Investigative Ophtalmology and Visual Science 2014 (Abstract).<\/li><li>Noda S, Hayasaka S, Setogawa T. Epiblepharon with inverted eyelashes in Japanese children. I. Incidence and symptoms. Br J Ophthalmol. 1989.<\/li><li>Park SK, Cho WK, Lee NY. Combined Periciliary Y-V Epicanthoplasty and Modified Hotz Procedure in Patients with Down Syndrome. Korean J Ophthalmol. 2020.<\/li><li>Rapport de la Soci\u00e9t\u00e9 Francaise d\u2019Ophalmonologie \u2013Ophalmologie P\u00e9diatrique Consult\u00e9 le 8\/08\/2022 sur Rapport SFO 2017 &#8211; OPHTALMOLOGIE P\u00c9DIATRIQUE (em-consulte.com).<\/li><li>Rork JF, McCormack L, Lal K, Wiss K, Belazarian L. Dermatologic conditions in Down syndrome: A single-center retrospective chart review. Pediatr Dermatol. 2020 .<\/li><li>Sathiamoorthi S, Frank RD, Mohney BG. Spontaneous Resolution and Timing of Intervention in Congenital Nasolacrimal Duct Obstruction. JAMA Ophthalmol. 2018 .<\/li><li>Singh M, Singh U. Bilateral congenital lacrimal fistula in Down syndrome. Middle East Afr J Ophthalmol. 2013.<\/li><li>Solomons G, Zellweger H, Jahnke Pg. Four Common Eye Signs In Mongolism. Am J Dis Child. 1965.<\/li><li>Stephen E, Dickson J, Kindley AD, Scott CC, Charleton PM. Surveillance of vision and ocular disorders in children with Down syndrome. Dev Med Child Neurol. 2007.<\/li><li>Tomita K, Tsurui H, Otsuka S, Kato K, Kimura A, Shiraishi Y, Shinbo Y, Takada K, Tomita A, Nomi Y. [Ocular findings in 304 children with Down syndrome]. Nippon Ganka Gakkai Zasshi. 2013.<\/li><li>Tsiaras WG, Pueschel S, Keller C, Curran R, Giesswein S. Amblyopia and visual acuity in children with Down&#8217;s syndrome. Br J Ophthalmol. 1999.<\/li><li>Ugurlu A, Altinkurt E. Ophthalmologic Manifestations and Retinal Findings in Children with Down Syndrome. J Ophthalmol. 2020.<\/li><li>Vagge A, Ferro Desideri L, Nucci P, Serafino M, Giannaccare G, Lembo A, Traverso CE. Congenital Nasolacrimal Duct Obstruction (CNLDO): A Review. Diseases. 2018.<\/li><li>Wang JJ, Lai CH, Kuo TY, Lin MH, Yang YH, Chen CY. Sex-speci\u00a6c effect of obesity on epiblepharon in different age groups: a case-control study. Research Square 2022 . doi.org\/10.21203\/rs.3.rs-1785240\/v1.<\/li><li>Watt T, Robertson K, Jacobs RJ. Refractive error, binocular vision and accommodation of children with Down syndrome. Clin Exp Optom. 2015.<\/li><li>Welham RA, Bates AK, Stasior GO. Congenital lacrimal fistula. Eye (Lond). 1992.<\/li><li>Wong V, Ho D. Ocular abnormalities in Down syndrome: an analysis of 140 Chinese children. Pediatr Neurol. 1997.<\/li><li>Young JD, MacEwen CJ, Ogston SA. Congenital nasolacrimal duct obstruction in the second year of life: a multicentre trial of management. Eye (Lond). 1996.<\/li><li>Zhang X, Li F, Rao J, Fang H, Zhu W. Spectrum of ophthalmic diseases in children hospitalized in a tertiary ophthalmology hospital in China from 2010 to 2019. BMC Ophthalmol. 2022.<\/li><li>Zhuo D, Chen S, Ren X, Wang B, Liu L, Xiao L. The prevalence of lower eyelid epiblepharon and its association with refractive errors in Chinese preschool children: a cross-sectional study. BMC Ophthalmol. 2021.<\/li><li>Makateb A, Hashemi H, Farahi A, Mehravaran S, Khabazkhoob M, Asgari S. Ocular alignment, media, and eyelid disorders in Down syndrome. Strabismus. 2020.<\/li><li>Markowitz GD, Handler LF, Katowitz JA. Congenital euryblepharon and nasolacrimal anomalies in a patient with Down syndrome. J Pediatr Ophthalmol Strabismus. 1994.<\/li><li>MacEwen CJ, Young JD. Epiphora during the first year of life. 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