{"id":1822,"date":"2022-03-16T18:35:54","date_gmt":"2022-03-16T17:35:54","guid":{"rendered":"https:\/\/t21learning.institutlejeune.org\/?p=1822"},"modified":"2023-11-22T17:16:14","modified_gmt":"2023-11-22T16:16:14","slug":"overweight-obesity-trisomy-21","status":"publish","type":"post","link":"https:\/\/t21learning.institutlejeune.org\/en\/overweight-obesity-trisomy-21\/","title":{"rendered":"Overweight and obesity"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"1822\" class=\"elementor elementor-1822\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6403dec elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6403dec\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-bd0b6df\" data-id=\"bd0b6df\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1a62ea0 elementor-widget elementor-widget-text-editor\" data-id=\"1a62ea0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>ENDOCRINE MANIFESTATIONS<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-29977f6 elementor-widget elementor-widget-heading\" data-id=\"29977f6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Overweight and Obesity\u200b<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6b81724 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6b81724\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-a9b9b46\" data-id=\"a9b9b46\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dcb356f elementor-widget elementor-widget-image\" data-id=\"dcb356f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"932\" height=\"572\" src=\"https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2022\/03\/Surpoids_obesite.jpeg\" class=\"attachment-large size-large wp-image-1859\" alt=\"\" srcset=\"https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2022\/03\/Surpoids_obesite.jpeg 932w, https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2022\/03\/Surpoids_obesite-300x184.jpeg 300w, https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2022\/03\/Surpoids_obesite-768x471.jpeg 768w\" sizes=\"(max-width: 932px) 100vw, 932px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-020f976\" data-id=\"020f976\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a7b1bfc elementor-widget elementor-widget-toggle\" data-id=\"a7b1bfc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1751\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1751\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">CHAPTER OUTLINE<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1751\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1751\"><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/thyroid-dysfunctions-trisomy-21\/\" target=\"_blank\" rel=\"noopener\">1- Thyroid dysfunctions<\/a><\/p><p>\u00a0<\/p><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/diabetes-mellitus\/\" target=\"_blank\" rel=\"noopener\">2- Diabetes mellitus<\/a><\/p><p>\u00a0<\/p><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/genital-functions\/\" target=\"_blank\" rel=\"noopener\">3- Genital functions<\/a><\/p><p>\u00a0<\/p><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/statural-growth\/\" target=\"_blank\" rel=\"noopener\">4- Statural growth<\/a><\/p><p>\u00a0<\/p><p><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/bone-health\/\">5- Bone health<\/a><\/p><p>\u00a0<\/p><p><strong><a href=\"https:\/\/t21learning.institutlejeune.org\/en\/overweight-obesity-trisomy-21\/\" target=\"_blank\" rel=\"noopener\">6- Overweight and obesity<\/a><\/strong><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-122386f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"122386f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8ad00be\" data-id=\"8ad00be\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f8c47a1 elementor-widget elementor-widget-text-editor\" data-id=\"f8c47a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>In the Western world, patients with trisomy 21 have a high risk of overweight and obesity. Almost 1 in 2 children and 3 in 4 adults are affected, i.e. the risk is 2-3 times higher than in the general population. This risk appears early, increases with age and often remains as people get older. It is higher for women than men.<\/p><p>\u00a0<\/p><p>In this video and accompanying technical sheet, Dr. Herv\u00e9 Walti, a pediatrician at the J\u00e9r\u00f4me Lejeune Institute, tells you more about: the critical periods of life for weight gain, the often self-aggravating risk factors, the consequences, and the ways to recognize and, of course, prevent it.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f16d585 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f16d585\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3905d11\" data-id=\"3905d11\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7143697 elementor-widget elementor-widget-video\" data-id=\"7143697\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/youtu.be\\\/cmG7HB56Dw4&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-35b1e35 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"35b1e35\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-50cec6a\" data-id=\"50cec6a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9a9ec15 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"9a9ec15\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/t21learning.institutlejeune.org\/wp-content\/uploads\/2023\/08\/1.6-Overweight-and-Obesity-EN.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Download the Summary Sheet<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c525fa2 elementor-widget elementor-widget-spacer\" data-id=\"c525fa2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e9ded71 elementor-widget elementor-widget-shortcode\" data-id=\"e9ded71\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\"><div class=\"_df_book df-lite\" id=\"df_2897\"  _slug=\"1-6-overweight-and-obesity-eng\" data-title=\"1-6-overweight-and-obesity-eng\" wpoptions=\"true\" thumbtype=\"\" ><\/div><script class=\"df-shortcode-script\" nowprocket type=\"application\/javascript\">window.option_df_2897 = {\"outline\":[],\"autoEnableOutline\":\"false\",\"autoEnableThumbnail\":\"false\",\"overwritePDFOutline\":\"false\",\"direction\":\"1\",\"pageSize\":\"0\",\"source\":\"https:\\\/\\\/t21learning.institutlejeune.org\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/6.-Overweight-and-Obesity_ENG.pdf\",\"wpOptions\":\"true\"}; if(window.DFLIP && window.DFLIP.parseBooks){window.DFLIP.parseBooks();}<\/script>\n<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b3b052b elementor-widget elementor-widget-spacer\" data-id=\"b3b052b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ee76b4a elementor-align-justify btn-refs elementor-widget elementor-widget-button\" data-id=\"ee76b4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">See references<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-9727192 div-refs div-refs-closed elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9727192\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5cf0724\" data-id=\"5cf0724\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-608a3f5 elementor-widget elementor-widget-text-editor\" data-id=\"608a3f5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>Alexander M, Petri H, Ding Y, Wandel C, Khwaja O, Foskett N. Morbidity and medication in a large population of individuals with Down syndrome compared to the general population. Dev Med Child Neurol. 2016 Mar;58(3):246-54. doi: 10.1111\/dmcn.12868. Epub 2015 Aug 18. PMID: 26282180.<\/li><li>Bertapelli F, Pitetti K, Agiovlasitis S, Guerra-Junior G. Overweight and obesity in children and adolescents with Down syndrome-prevalence, determinants, consequences, and interventions: A literature review. Res Dev Disabil. 2016 Oct;57:181-92. doi: 10.1016\/j.ridd.2016.06.018. Epub 2016 Jul 19. PMID: 27448331.<\/li><li>Hatch-Stein JA, Zemel BS, Prasad D, Kalkwarf HJ, Pipan M, Magge SN, Kelly A. Body Composition and BMI Growth Charts in Children With Down Syndrome. Pediatrics. 2016 Oct;138(4):e20160541. doi: 10.1542\/peds.2016-0541. Epub 2016 Sep 14. PMID: 27630073; PMCID: PMC5051207.<\/li><li>Mircher C, Brice\u00f1o LG, Toulas J, Conte M, Tanguy ML, Cieuta-Walti C, Rethore MO, Ravel A. Growth curves for French people with Down syndrome from birth to 20\u2009years of age. Am J Med Genet A. 2018 Dec;176(12):2685-2694. doi: 10.1002\/ajmg.a.40639. Epub 2018 Dec 20. PMID: 30569664.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-0fd8886\" data-id=\"0fd8886\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8240ddd elementor-widget elementor-widget-text-editor\" data-id=\"8240ddd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>Pierce M, Ramsey K, Pinter J. Trends in Obesity and Overweight in Oregon Children With Down Syndrome. Glob Pediatr Health. 2019 Apr 2;6:2333794X19835640. doi: 10.1177\/2333794X19835640. PMID: 31044152; PMCID: PMC6446252.<\/li><li>Ravel A, Mircher C, Rebillat AS, Cieuta-Walti C, Megarbane A. Feeding problems and gastrointestinal diseases in Down syndrome. Arch Pediatr. 2020 Jan;27(1):53-60. doi: 10.1016\/j.arcped.2019.11.008. Epub 2019 Nov 26. PMID: 31784293.<\/li><li>Susan M Havercamp, Marc J. Tass\u00e9 , Patricia Navas, Betsey A Benson, Dawn Allain, Kandamurugu Manickam. Exploring the Weight and Health Status of Adults with Down Syndrome Journal of Education and Training Studies 5, No. 6; June 2017,97-108<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-c8b95a8 elementor-widget elementor-widget-html\" data-id=\"c8b95a8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<script>\n    jQuery(\".btn-refs\").on(\"click\", function(e){\n        e.preventDefault()\n        jQuery(\".div-refs\").toggleClass(\"div-refs-closed\")\n    })\n<\/script>\n\n<style>\nbody:not(.elementor-editor-active) .div-refs{\n    transition: 0.3s;\n    max-height: 1000px;\n}\n    body:not(.elementor-editor-active) .div-refs-closed{\n        max-height: 0;\n        overflow: hidden !important;\n    }\n<\/style>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>ENDOCRINE MANIFESTATIONS Overweight and Obesity\u200b CHAPTER OUTLINE 1- Thyroid dysfunctions \u00a0 2- Diabetes mellitus \u00a0 3- Genital functions \u00a0 4- Statural growth \u00a0 5- Bone health \u00a0 6- Overweight and obesity In the Western world, patients with trisomy 21 have a high risk of overweight and obesity. Almost 1 in 2 children and 3 in [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":1859,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[2],"tags":[],"thematique":[48],"type_contenu":[55],"class_list":["post-1822","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medecin","thematique-medical-and-paramedical","type_contenu-video-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Overweight and obesity - t21learning<\/title>\n<meta name=\"description\" content=\"ENDOCRINE MANIFESTATIONS Overweight and Obesity\u200b CHAPTER OUTLINE 1- Thyroid dysfunctions\u00a02- Diabetes mellitus\u00a03- Genital functions\u00a04- Statural growth\u00a05-\" \/>\n<meta name=\"robots\" content=\"index, follow, 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